Home page problems for some users - 5.0.2/5.0.4 - Can't edit

I’m seeing an odd quirk with a few users post 5.0.2/5.0.4 upgrade (from 4.4.6). I’ve had a small handful of users tell me that post upgrade, they can’t make changes to their home page (add new widgets, etc). I’ve set ModifySelf to yes for all Privileged users of which this user is a member.

This isn’t happening to all users. Any ideas on what I can check?